A comprehensive approach to Psychedelic Enhanced Psychotherapy

Psychedelic medicine should enhance psychotherapy, not replace it.

Psychedelics like ketamine work best when combined with other evidence-based interventions provided by a trained mental health practitioner.

Many existing psychedelic therapy clinics encourage “self-guided” psychedelic experiences, where practitioners are present to ensure a patient's physical safety, but are not equipped to engage with them therapeutically during the session.

We take a different approach. TRIP™-certified therapists are trained to actively engage patients in a more structured, intentional psychedelic-enhanced psychotherapy session.

This allows psychedelic medicine to work the way it’s meant to: as a compliment to psychotherapy, and a catalyst for discovery and healing.

There are 5 steps to the TRIP Protocol

Training at MindSetting Institute will empower you to confidently support patients through each phase.


Assessing patients to determine suitability.

Identifying any physical or psychological contraindications for ketamine use

Conducting a personality assessment

Determining severity of major depressive, generalized anxiety, obsessive-compulsive or post-traumatic stress disorders

Appraising their position along the continuum of the stages of change

Treatment Planning

Conducting a treatment planning session to set patients up for success.

Relaxation skills and necessary training

Mindfulness skills and necessary training

Identification of short term and long term goals

Ketamine Therapy

Guiding patients through a psychedelic-enhanced psychotherapy session.

Overseeing patients as they self-administer the prescribed dose of oral ketamine

Understanding how to engage patients in psychotherapy while they are under the influence of ketamine

Carefully transcribing notes to refer back to during the integration sessions


Analyzing the PEP session transcript using established psychological theories:

Using insight-oriented theory, cognitive-behavioural principles, and constructivist grounded theory to analyze PEP transcripts

Extracting key themes, core beliefs, and stimulus-response associations

Developing a summary of these findings to present to patients during the integration session


Guiding patients through integration sessions that lead to emotional, cognitive, and behavioural change.

Supporting patients as they share their reflections, thoughts, and experiences of the PEP session

Presenting your analysis of the PEP session transcript

Co-constructing with patients further interpretations of the experience and data

Working with patients to develop behaviour modification strategies informed by the PEP experience

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